发明名称 |
Materials and methods for detection of insulin dependent diabetes |
摘要 |
The method and compositions of this invention provide an effective and reliable substitute for the currently employed ICA assay for diabetes. By providing a method for detecting autoantibodies to both GAD65 and IA-2 auto-antigens, the method provides a chemical assay which has improved reliability. In addition, these antigens may be employed in therapeutic regimens aimed at achieving immune tolerance and therefore amelioration of the clinical condition.
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申请公布号 |
US6391651(B1) |
申请公布日期 |
2002.05.21 |
申请号 |
US19950514213 |
申请日期 |
1995.08.11 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH & HUMAN SERVICES;UNIVERSITY OF FLORIDA |
发明人 |
MACLAREN NOEL K.;NOTKINS ABNER L.;LAN MICHAEL S. |
分类号 |
A61K38/00;A61K39/00;C07K14/47;C07K14/705;C12N9/16;(IPC1-7):G01N33/564 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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