| 摘要 |
Drugs, in particular, anticancer agents. More particularly speaking, anticancer agents which contain as the active ingredient(s) one or more compounds selected from among .omega.-hydroxyfatty acids having a specific chemical structural formula and salts and esters thereof, hydroxyoxofatty acids and salts and esters thereof, lactone compounds, macrocyclic ketones a nd macrocyclic diesters. The above-described compounds have a carcinostatic effect, an extremely high effect of preventing cancer metastasis, an effect of preventing recurrence of cancer, an effect of preventing the occurrence of cancer and little cytotoxicity. Moreover, these compounds are efficacious on ly in a small dose. Owing to these characteristics, these compounds enable the provision of anticancer agents with little side effect. The effect of preventing cancer metastasis can be further enhanced by the combined use wit h known anti-malignant tumor agents. Among the anticancer agents as described above, .omega.-hydroxyfatty acids can be very conveniently obtained at a hig h purity by hydrolyzing lactone compounds which are also the anticancer agents as described herein.
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