| 发明名称 |
3-INDOLYL-4-PHENYL-1H-PYRROLE-2,5-DIONE DERIVATIVES AS INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3BETA |
| 摘要 |
The present invention relates to 3-indolyl-4-phenyl-1H-pyrrole-2,5-dione derivatives of Formula (I), wherein R<1> to R<6> have the value given in the specification. The compounds are useful as inhibitors of glycogen synthase kinase-3 beta and, therefore, may be used for the treatment of GSK-3 beta mediated diseases. |
| 申请公布号 |
WO0210158(A3) |
申请公布日期 |
2002.05.16 |
| 申请号 |
WO2001EP08293 |
申请日期 |
2001.07.18 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
GONG, LEYI;GRUPE, ANDREW;PELTZ, GARY, ALLEN |
| 分类号 |
A61K31/404;A61K31/4178;A61K31/454;A61K31/5377;A61K31/695;A61P3/04;A61P3/10;A61P7/02;A61P9/10;A61P11/02;A61P11/06;A61P15/00;A61P17/02;A61P25/00;A61P25/18;A61P25/28;A61P35/00;A61P37/02;A61P37/08;A61P43/00;C07D401/14;C07D403/04;C07D403/14;C07D405/14 |
主分类号 |
A61K31/404 |
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