发明名称 |
METHOD FOR PREPARING 1,3-PROPANEDIOL BY A RECOMBINANT MICRO-ORGANISM IN THE ABSENCE OF COENZYME B12 OR ONE OF ITS PRECURSORS |
摘要 |
The invention concerns a method for preparing 1,3-propanediol from a carbon-containing substance, said method comprising a step which consists in culturing a recombinant micro-organism not producing coenzyme B12 in the absence of coenzyme B12 or one of its precursors. The invention also concerns a nucleic acid coding for a glycerol dehydratase whereof the catalytic activity is independent of the presence of coenzyme B12 or one of its precursors and a nucleic acid coding for a 1,3-propanol dehydrogenase intervening in the synthesis of 1,3-propanediol. The invention further concerns recombinant vectors and host cells comprising said nucleic acids and the polypeptides coded by the latter. |
申请公布号 |
EP1200597(A1) |
申请公布日期 |
2002.05.02 |
申请号 |
EP20000949686 |
申请日期 |
2000.07.07 |
申请人 |
INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA);INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE |
发明人 |
SARCABAL, PATRICIA;CROUX, CHRISTIAN;SOUCAILLE, PHILIPPE |
分类号 |
C12N1/19;C12N1/21;C12N9/88;C12N15/53;C12N15/60;C12P7/18 |
主分类号 |
C12N1/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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