SURVIVIN-LIKE POLYPEPTIDES AND DNAS THEREOF

摘要

It is intended to provide survivin-like polypeptides and DNAs thereof. Polypeptides having an amino acid sequence which is the same or substantially the same as an amino acid sequence represented by SEQ ID NO:5 or SEQ ID NO:9, amides, esters or salts thereof; DNAs containing DNAs encoding these polypeptides; recombinant vectors containing these DNAs; transformants transformed by these recombinant vectors; drugs containing the above polypeptides, amides, esters or salts thereof; antibodies against the above polypeptides, amides, esters or salts thereof; a method of screening a compound or its salt having an activity of inhibiting the caspase activity of the above polypeptides, amides, esters or salts thereof; etc.