Desalting and purification of oligosaccharides and their derivatives

摘要

A preparative method of separating oligosaccharides from contaminants such as peptides and salts, comprising the steps of reacting a solution containing oligosaccharides and contaminants with a solid support comprising graphitized carbon such that the oligosaccharides substantially bind to the solid support; washing the support to remove any contaminants not bound to the solid support; and eluting the bound oligosaccharide from the support without eluting bound contaminants to obtain a solution of oligosaccharides substantially free of contaminants.