N-(4-ARYLOXYPIPERIDIN-1-YLALKYL) CINNAMIC AMIDES AS CCR3 RECEPTOR ANTAGONISTS

摘要

Compounds of formula (I) in free or salt form, where Ar<1> is phenyl substituted by one or more substituents selected from halogen, cyano, nitro, and C1-C8-alkyl optionally substituted by cyano or halogen, Ar<2> is phenyl or naphthyl which is substituted by one or more substituents selected from halogen, cyano or C1-C8-alkoxy, R<1> is hydrogen or C1-C8-alkyl, and n is 1, 2, 3 or 4. The compounds are useful as pharmaceuticals.