| 摘要 |
<p>The invention relates to a sequence of amino acids with the capacity to facilitate transport of an effector across a biological membrane. More specifically, the present invention relates to novel peptide transporter that specifically target certain cell types for the intracellular delivery of drugs and therapeutic agents, comprising at least one amino acid sequence selected from the group consisting of: a) (XmRXoRXn); b) (XmRRRXn); c) (XmRRXRXn); and d) (XmRXRRXn), wherein X is a non-basic amino acid; m is an integer from zero to fourteen; n is an integer, independent of m, between zero and fourteen; o is an integer, independent of m and n, between zero and five; and wherein said transporter peptide is capable of translocating across a biological membrane.</p> |
