发明名称 Aminoaklanoyl-linked conjugates of 2',5'-oligoadenylate and antiviral uses thereof
摘要 Antiviral compounds and the water-soluble salts thereof have formula (I), wherein n is from 1 to 8; R1 is selected from the group consisting of (a), wherein m is zero, 1, 2 or 3; and (b), wherein q is from 1 to 20; R2 is independently selected from the group consisting of oxygen and sulfur; R3 is independently selected from the group consisting of hydrogen and hydroxyl; and R4 is selected from the group consisting of hydrogen, hydroxyl and (b); R5 is selected from the group consisting of hydroxyl and (b); R6 is selected from the group consisting of (c), (d) et (e), wherein x is from 1 to 20; provided that one of R1, R4 and R5 is (b) wherein R6 is defined as above; or water soluble salt thereof.
申请公布号 US6362171(B1) 申请公布日期 2002.03.26
申请号 US19990445559 申请日期 1999.12.09
申请人 TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 发明人 SUHADOLNIK ROBERT J.;PFLEIDERER WOLFGANG
分类号 C07H21/00;(IPC1-7):A61K31/505;A61K31/675;C07D403/14;C07H21/04 主分类号 C07H21/00
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