| 摘要 |
<p>Zofimarin derivatives having an excellent antifungal activity, and pharmacologically acceptable esters and pharmacologically acceptable salts thereof; medicinal compositions (in particular, antifungal agents) containing the same as the active ingredient; use of these derivatives, esters or salts for producing these medicinal compositions; and a method of preventing or treating diseases (in particular, fungal infections) by administering a pharmacologically effective dose of these derivatives, esters or salts to warm blood animals (in particular, human beings). The zofimarin derivatives as described above are represented by the following general formula (I) wherein R1 represents formyl, etc.; R?2 and R3¿ independently represent each C¿1-6? alkyl, etc.; and R?4¿ represents hydrogen, etc.</p> |
