SOLUBLE COMPOUNDS FOR THE INHIBITION OF MULTIDRUG RESISTANCE AND PHARMACEUTICAL COMPOSITIONS THEREOF

摘要

The invention relates to compounds of general formula (I) wherein T represents a chemical bond; a piperidyl group optionnally substituted with 1-8 substituents selected independently from C1-6 alkyl and C1-6 alkoxy groups; or a pyrrolidyl group optionally substituted with 1-6 substituents selected independently from C1-6 alkyl and C1-6 alkoxy groups; and X represents an acyl group derived from an amino acid protected on its functional group(s); their pharmaceutically acceptable salts and pharmaceutical compositions thereof. The compounds of the present invention are capable for the inhibition of resistance developed against certain therapeutic agents in a patient.