| 发明名称 |
TRUNCATED CRAFI INHIBITS CD40 SIGNALING |
| 摘要 |
Overexpression of a CRAF1 (CD40 receptor-associated factor 1) gene truncated by 323 to about 414 amino acids at the amino inhibits CD40-mediated cell activation, and is used to treat conditions characterized by an unwanted level of CD40-mediated intracellular signaling.
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| 申请公布号 |
US2002031522(A1) |
申请公布日期 |
2002.03.14 |
| 申请号 |
US19970813323 |
申请日期 |
1997.03.10 |
| 申请人 |
BALTIMORE DAVID;CHENG GENHONG;YE ZHENG-SHENG;LEDERMAN SETH;CLEARY AILEEN |
发明人 |
BALTIMORE DAVID;CHENG GENHONG;YE ZHENG-SHENG;LEDERMAN SETH;CLEARY AILEEN |
| 分类号 |
A61K38/00;C07K14/715;(IPC1-7):G01N33/53;G01N33/567;G01N33/574;C12P31/00;C12P29/00;A61K39/00;C07K5/00;C07K7/00;C07K16/00;C07K17/00;C07K1/00;C07K14/00;A61K38/16 |
主分类号 |
A61K38/00 |
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