METHOD FOR ANALYSIS OF METABOLIC PATHWAYS

摘要

This invention relates to methods for the analysis of metabolic pathways and the effect of perturbation or applied stimuli on metabolic pathways. The method involves perturbing a system, for example, by a xenobiotic, a disease state or genetic modification, labelling at least one small endogenous small molecule to be incorporated into a metabolic pathway in the system, analysing samples from the perturbed system to determine the time-related incorporation of the labelled molecule and then comparing the data thus obtained with data obtained from a corresponding unperturbed system, for example, using pattern recognition techniques.