| 发明名称 |
ERBB4 ANTAGONISTS |
| 摘要 |
<p>The present invention concerns methods and means for controlling excessive proliferation and/or migration of smooth muscle cells, and in particular for treating stenosis, by using antagonists of a native ErbB4 receptor. The invention further concerns a method for the identification of ErbB4 agonists and antagonists capable of inhibiting or enhancing the proliferation or migration of smooth muscle cells.</p> |
| 申请公布号 |
CA2420062(A1) |
申请公布日期 |
2002.03.07 |
| 申请号 |
CA20012420062 |
申请日期 |
2001.08.29 |
| 申请人 |
GENENTECH, INC. |
发明人 |
SLIWKOWSKI, MARK X.;GERRITSEN, MARY E. |
| 分类号 |
G01N33/50;A61K38/00;A61K39/395;A61K45/00;A61K48/00;A61P9/00;A61P9/12;A61P13/10;A61P21/00;C07K14/475;C07K14/82;C07K16/32;C07K16/40;C12N15/02;C12P21/08;G01N33/15;G01N33/53;G01N33/566;(IPC1-7):C07K16/00 |
主分类号 |
G01N33/50 |
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