ANTI-IGE VACCINES

摘要

The present invention provides compositions and methods for the use of
antigenic
peptides derived from the Fc portion of the epsilon heavy chain of an IgE
molecule as
vaccines for the treatment and prevention of IgE-mediated allergic disorders.
In particular,
the invention provides compositions, methods for the treatment and prevention
of
IgE-mediated allergic disorders comprising an immunogenic amount of one or
more antigenic
peptides derived from the CH3 domain or junction of Ch-3/CH4 domain of an IgE
molecule
and methods for the evaluation of IgE mediated allergies in dogs.