Avermectin derivatives

摘要

A compound represented by the general formula (I) or a salt thereof: wherein, -XY- represents -CH=CH-, -CH2-CH2- or the like, between R<1 >and the carbon atom at 4'-position represents a single bond or a double bond, between R<2 >and the carbon atom at 5-position represents a single bond or a double bond, and for example, 1) when -XY- represents -CH=CH- or -CH2-CH2-, and between R<1 >and the carbon atom at 4'-position represents a double bond, R<1 >represents =C(R<11>)(R<12>) (wherein R<11 >represents a lower alkyl group or the like and R<12 >represents a hydrogen atom or the like) or the like, and R<2 >represents a hydroxyl group or the like, or R<2 >may be combined together with the carbon atom at 5-position to form a carbonyl group, and 2) when -XY- represents -CH=CH- or -CH2-CH2-, and between R<1 >and the carbon atom at 4'-position represents a single bond, R<1 >represents -OCH(R<1a>)(R<1b>) (wherein R<1a >represents a lower alkyl or the like and R<1b >represents a hydrogen atom or the like) or the like, and R<2 >represents a hydroxyl group or the like.