| 摘要 |
<p>PCT No. PCT/GB95/01249 Sec. 371 Date May 23, 1997 Sec. 102(e) Date May 23, 1997 PCT Filed May 31, 1995 PCT Pub. No. WO95/32966 PCT Pub. Date Dec. 7, 1995A compound of formula (I), wherein A is C1-6alkyl, -O-C1-6alkyl, -O-phenyl or phenyl, optionally substituted by C1-3alkyl or halogen; n is an integer of from 0 to 3; W is a group of formula (i), (ii) or (iii) where R is hydrogen or C1-4alkyl, x is -O-, -S-, -NH-, or -CH2-, Y is oxygen or sulphur and the chiral centre * in formula (i) or (ii) is in its (S) or (R) form or is a mixture thereof in any proportions; and Z is a group of formula (iv) -HC2CH2NR1R2(v) or (vi) where R1 and R2 are independently selected from hydrogen and C1-4alkyl and R3 is hydrogen or C1-4alkyl; and salts, solvates and physiologically functional derivatives thereof.</p> |
