BSTP-TRANS PROTEIN AND RELATED REAGENTS AND METHODS OF USE THEREOF

摘要

The invention provides a protein (BSTP-TRANS) and polynucleotides which identify and encode BSTP-TRANS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. In addition, the invention provides methods for treating or preventing disorders of cell proliferation, particularly breast cancer, by administering a pharmaceutical composition comprising a polypeptide, polynucleotide, or antibody of the invention. The invention also provides methods of classifying diseases, particularly breast cancer, by detecting expression of BSTP-TRANS or of a polynucleotide encoding BSTP-TRANS, and methods of providing diagnostic, prognostic, and/or predictive information for a patient based on the detection and/or measurement of BSTP-TRANS or of a gene that encodes BSTP-TRANS or of a mutation in the BST-TRANS gene.