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发明名称
一种新的抗肿瘤活性物质
摘要
本发明公开了一种肿瘤细胞抑制剂。其为4-(2-氨基乙基)-苯酚(俗名酪胺),是一种内源性代谢产物,可由组织细胞分泌。酪胺能不可逆地抑制多种属、多组织来源的恶性肿瘤细胞,而对人及小鼠正常细胞或正常来源的细胞系抑制较弱,呈现一定的选择性。酪胺对小鼠移植性肿瘤具有一定程度的治疗作用:常规腹腔给药,抑制率可达30%~40%。酪胺具有作为肿瘤细胞抑制剂的新用途,从而为临床上治疗肿瘤提供了新的方法和手段。
申请公布号
CN1331969A
申请公布日期
2002.01.23
申请号
CN00109454.8
申请日期
2000.06.26
申请人
中国人民解放军军事医学科学院放射医学研究所
发明人
张津辉;吴祖泽;王艳飞
分类号
A61K31/137;A61P35/00
主分类号
A61K31/137
代理机构
代理人
主权项
1.具有下述结构的4-(2-氨基乙基)-苯酚(俗名酪胺),在制备肿瘤抑制剂及抗肿瘤药物中的用途,该物质与普通药用载体或赋形剂组合用于制备通过不可逆地杀伤肿瘤细胞所起作用的抗肿瘤药物。<img file="A0010945400021.GIF" wi="990" he="691" />
地址
100850北京市太平路27号院二所
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