发明名称 |
Methods and compositions for use of catalase in hydrogels and biosensors |
摘要 |
Hydrogels containing catalase co-immobilized with an analyte-sensitive enzyme such as glucose oxidase are disclosed. The hydrogels may be pH-sensitive, and preferably are thin and lightly crosslinked. The catalase is present in concentrations ranging generally from 100 units/ml to about 1000 units/ml. These hydrogels have much faster swelling response times as compared to hydrogels without catalase, and are useful in biosensors and analyte-responsive drug delivery devices. The hydrogels also have an increased useful life, due to protection of the immobilized analyte-sensitive enzyme from degradation by hydrogen peroxide.
|
申请公布号 |
US2002006634(A1) |
申请公布日期 |
2002.01.17 |
申请号 |
US20010824552 |
申请日期 |
2001.04.02 |
申请人 |
HAN IN SUK;JUNG DAL-YOUNG |
发明人 |
HAN IN SUK;JUNG DAL-YOUNG |
分类号 |
A61B5/00;C12N11/18;C12Q1/00;G01N7/00;G01N13/04;(IPC1-7):A61K38/44;C12Q1/26;A61K9/14 |
主分类号 |
A61B5/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|