RECEPTOR BINDING MOLECULES

摘要

Disclosed is a receptor binding molecule comprising an incomplete portion of a colicin R domain, the incomplete portion comprising fewer than 300 amino acid residues of the colicin R domain yet nevertheless retaining the receptor binding activity of the complete R domain, and comprising at least amino acid residues 343-418 of colicin E9 or the equivalent residues of the R domain of another colicin, the equivalent residues being determined by sequence alignment using the program Megalign, with the alignment being maximised by the CLUSTAL method.