Method for producing hexahydro-2-OXO-1H-thieno[3,4-D]imidazole-4-pentanoic acid

摘要

There is disclosed a process for producing hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid of the formula (2):which is characterized by contacting a compound of the formula (1):wherein R1 and R2 represent a hydrogen atom or a benzyl group, but R1 and R2do not simultaneously represent a hydrogen atom, and R3 represents a hydrogen atom or a carboxyl group, with sulfuric acid in the presence of an aromatic hydrocarbon.