发明名称 |
ANTI-INFLAMMATORY TOLEROGENIC AND IMMUNOINHIBITING PROPERTIES OF CARBOHYDRATE BINDING-PEPTIDES |
摘要 |
<p>The present invention is directed to lectin derived carbohydrate binding peptides or derivatives thereof useful for suppressing inflammatory responses, inducing tolerance to an antigen, and suppressing cell adhesion, e.g., involved in metastasis. In particular, peptides capable of binding terminally linked alpha-sialic acid(2-6)betaGal- and/or alpha-sialic acid(2-3)betaGal-groups on structures or molecules comprising such groups are provided. Pharmaceutical compositions containing such lectin derived carbohydrate binding peptides are also disclosed.</p> |
申请公布号 |
EP0666758(B1) |
申请公布日期 |
2001.12.12 |
申请号 |
EP19930921770 |
申请日期 |
1993.10.04 |
申请人 |
ALBERTA RESEARCH COUNCIL |
发明人 |
HEERZE, LOUIS, D.;ARMSTRONG, GLEN, D.;SMITH, RICHARD |
分类号 |
A61K38/36;A61K38/00;A61K38/16;A61K38/46;A61K38/47;A61K39/35;A61P1/00;A61P9/00;A61P11/00;A61P15/04;A61P29/00;A61P37/00;C07K7/06;C07K14/235;C07K14/42;(IPC1-7):A61K38/02 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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