188RE-LABELLED 5-THIO-D-GLUCOSE FOR RADIONUCLEOTIDE TUMOR THERAPY

摘要

The present invention is related to a radiopharmaceutical comprising a 5-thio-D-Glucose molecule labeled with a <188>Re isotope for use in radionuclide tumor therapy; to a composition for radionuclide therapy comprising the radiopharmaceutical; and a method of preparing the radiopharmaceutical; and to a method of preparing the radiopharmaceutical, comprising the step of combining 5-thio-D-Glucose, stannous ions, and a solution of <188>Re isotope in a pharmaceutically acceptable solvent. This radiopharmaceutical is generally applicable to the majority of the different types of tumors related to the different types of cancer, and it is efficiently cleared from the body after the therapeutic use.