发明名称 |
Compositions and methods for treating sexual dysfunctions |
摘要 |
The present invention describes methods for preventing and treating sexual dysfunctions in patients by orally administering at least one alpha-adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo. The present invention also describes orally administrable compositions comprising at least one alpha-adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo. In the present invention, the alpha-adrenergic receptor antagonist is preferably yohimbine or phentolamine, and the compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo is preferably L-arginine.
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申请公布号 |
US6323211(B1) |
申请公布日期 |
2001.11.27 |
申请号 |
US19990285048 |
申请日期 |
1999.04.02 |
申请人 |
NITROMED, INC. |
发明人 |
GARVEY DAVID S.;SCHROEDER JOSEPH D.;DE TEJADA INIGO SAENZ |
分类号 |
A61K31/475;A61K45/06;C07C381/00;C07D211/62;C07D233/24;C07D239/95;C07D401/04;C07D405/12;C07D459/00;(IPC1-7):A61K31/44;A61K31/195 |
主分类号 |
A61K31/475 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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