发明名称 Compositions and methods for treating sexual dysfunctions
摘要 The present invention describes methods for preventing and treating sexual dysfunctions in patients by orally administering at least one alpha-adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo. The present invention also describes orally administrable compositions comprising at least one alpha-adrenergic receptor antagonist and at least one compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo. In the present invention, the alpha-adrenergic receptor antagonist is preferably yohimbine or phentolamine, and the compound that elevates endogenous nitric oxide or endothelium-derived relaxing factor in vivo is preferably L-arginine.
申请公布号 US6323211(B1) 申请公布日期 2001.11.27
申请号 US19990285048 申请日期 1999.04.02
申请人 NITROMED, INC. 发明人 GARVEY DAVID S.;SCHROEDER JOSEPH D.;DE TEJADA INIGO SAENZ
分类号 A61K31/475;A61K45/06;C07C381/00;C07D211/62;C07D233/24;C07D239/95;C07D401/04;C07D405/12;C07D459/00;(IPC1-7):A61K31/44;A61K31/195 主分类号 A61K31/475
代理机构 代理人
主权项
地址