PROCESSO PARA A PREPARACAO DE RIBOFLAVINA POR MEIO DE MICROORGANISMOS COM ACTIVIDADE DE ISOCITRATOLIASE MODIFICADA

摘要

PCT No. PCT/EP96/03009 Sec. 371 Date May 1, 1998 Sec. 102(e) Date May 1, 1998 PCT Filed Jul. 10, 1996 PCT Pub. No. WO97/03208 PCT Pub. Date Jan. 30, 1997The disclosure concerns a process for the microbial preparation of riboflavin by culturing riboflavin-producing microorganisms in a nutrient medium and then isolating the riboflavin which has been produced, which comprises using microorganisms in which the endogenous isocitrate lyase (ICL) activity has been altered.