发明名称 |
Method of inducing tumor cell apoptosis using trail/apo-2 ligand gene transfer |
摘要 |
The present invention is directed to methods for inhibiting tumor cell growth, causing tumor regression or eliminating tumor cells in a mammal afflicted with a tumor by administering to a TRAIL-sensitive cell a vector having a DNA expression cassette containing a promoter and a DNA sequence encoding TRAIL, wherein the expression of TRAIL results in tumor inhibition, regression or elimination. |
申请公布号 |
AU5154401(A) |
申请公布日期 |
2001.10.30 |
申请号 |
AU20010051544 |
申请日期 |
2001.04.11 |
申请人 |
UNIVERSITY OF IOWA RESEARCH FOUNDATION |
发明人 |
THOMAS S. GRIFFITH;TIMOTHY RATLIFF |
分类号 |
A61K38/17;A61K48/00;A61P35/00;C07K14/705;C12N15/12;(IPC1-7):C12N15/12 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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