发明名称 SELF-EXTINGUISHING RECOMBINASES, NUCLEIC ACIDS ENCODING THEM AND METHODS OF USING THE SAME
摘要 <p>Nucleic acid molecules comprising at least a first signal site and a recombinase gene operably linked to an expression control sequence, such that upon entry into a cell, there is a first signal site and a second signal site positioned to mediate excision of a sufficient portion of either the recombinase gene or the expression control sequence to extinguish recombinase activity when the first and second signal sites are contacted with a recombinase, cells, transgenics and uses of the foregoing.</p>
申请公布号 WO2001079471(A2) 申请公布日期 2001.10.25
申请号 US2001012193 申请日期 2001.04.12
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