| 发明名称 |
Substituted amino acids as neutral sphingomyelinase inhibitors |
| 摘要 |
This invention relates to a series of substituted amino acids of Formula Ipharmaceutical compositions containing them and intermediates used in their manufacture. The compounds of the invention are small molecules that bind to neutral sphingomyelinase and inhibit its activity.
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| 申请公布号 |
US6306911(B1) |
申请公布日期 |
2001.10.23 |
| 申请号 |
US20000499426 |
申请日期 |
2000.02.07 |
| 申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC. |
发明人 |
WACHTER MICHAEL P.;LALAN PRAFUL |
| 分类号 |
A61K31/19;A61K31/197;A61K31/22;A61K31/405;A61K31/415;A61K31/435;A61K31/4709;A61K38/00;A61K38/55;A61P3/10;A61P9/10;A61P19/02;A61P29/00;A61P35/00;A61P43/00;C07C229/14;C07C229/22;C07D209/20;C07D215/12;C07D231/38;C07K5/06;C07K5/072;(IPC1-7):A61K31/195;A61K31/381;A61K31/470;C07C229/00;C07C237/06;C07D401/12 |
主分类号 |
A61K31/19 |
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