发明名称 |
Template-directed photoligation |
摘要 |
Methods, apparatus and compositions are presented for ligating ligands together which bind to a common receptor. One embodiment includes polynucleotide probes having photoreactive functional groups. The probes are capable of assuming substantially contiguous reactive positions on a target polynucleotide placing the photoreactive group in juxtaposition. Activation of the photoreactive functional groups with radiant energy form a probe reaction product in which the probes are bound to each other.
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申请公布号 |
US6306587(B1) |
申请公布日期 |
2001.10.23 |
申请号 |
US19970967011 |
申请日期 |
1997.11.10 |
申请人 |
VYSIS, INC. |
发明人 |
ROYER GARFIELD P.;MORRISON LARRY E.;CRUICKSHANK KENNETH A. |
分类号 |
G01N33/50;C07D311/14;C07D311/16;C07D311/18;C07D493/04;C07H21/04;C12N15/09;C12Q1/68;(IPC1-7):A01N1/02;G01N15/06;A01K51/00;C07H19/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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