Transdermal therapeutic system (TTS) for the transcutaneous administration of oxybutynin

摘要

A transdermal therapeutic system (TTS) for the transcutaneous administration of oxybutynin over a period of at least one day. The TTS contains a self-adhesive layer-form oxybutynin-containing matrix mass, which comprises an ammonium-group-containing (meth)acrylate copolymer, at least one citric acid triester and 5-25 weight percent of oxybutynin. The TTS may also contain an attachment aid for attaching the TTS onto the skin, where the matrix mass is surrounded by a larger, active-ingredient-free plaster for attachment onto the skin, with the exception of its release surface, at the application site.