发明名称 |
VARIATION IN DRUG RESPONSE RELATED TO POLYMORPHISMS IN beta 2- ADRENERGIC RECEPTOR |
摘要 |
<p>A method for predicting an individual's response to the ss-agonists salmeterol, albuterol, metaproterenol, terbutaline and formoterol is disclosed. Individuals expressing the Ile164 ss2AR variant are likely to exhibit a reduced response as compared to individuals expressing the Thr164 ss2AR variant. The method is useful for making treatment decisions for patients suffering from asthma and chronic obstructive pulmonary diseases.</p> |
申请公布号 |
WO0106910(A3) |
申请公布日期 |
2001.09.27 |
申请号 |
WO2000US06502 |
申请日期 |
2000.03.10 |
申请人 |
UNIVERSITY OF CINCINNATI;LIGGETT, STEPHEN, B. |
发明人 |
LIGGETT, STEPHEN, B. |
分类号 |
C07K14/705;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/04 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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