| 发明名称 |
NOVEL PROCESS FOR PREPARING (+)-CIS-SERTRALINE |
| 摘要 |
The present invention is directed to (+)-cis-sertraline hydrochloride and methods of preparation. The present invention also includes processes for making sertraline having a cis/trans ratio greater than 3:1, greater than or equal to 8:1, or between about 8:1 and about 12:1, from the Schiff base of sertralone, sertraline-1-imine.
|
| 申请公布号 |
CA2402656(A1) |
申请公布日期 |
2001.09.20 |
| 申请号 |
CA20012402656 |
申请日期 |
2001.03.14 |
| 申请人 |
TEVA PHARMACEUTICAL INDUSTRIES LTD. |
发明人 |
GERSHON, NEOMI;MENDELOVICH, MARIUARA;NIDAM, TAMMMY;PILARSKY, GIDEON |
| 分类号 |
C07B57/00;C07B61/00;C07C209/52;C07C209/88;C07C211/42;(IPC1-7):C07B57/00 |
主分类号 |
C07B57/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
