The subject matter of the invention is the use of ÄaÜ bicycloheptane derivative(s) of formula <CHEM> wherein R represents a phenyl or a benzyl group, R1 and R2 , which may be the same or different stand for straight or branched chained alkyl groups or one of R1 and R2 is hydrogen and the other is a straight or branched chained alkyl group, A denotes a straight or branched chained alkylene group and SIMILAR represents a valence bond, and ÄanÜ N-oxide(s) as well as ÄanÜ optical isomer(s) thereof and mixtures of the optical isomers and ÄanÜ acid addition salt(s) and quaternary ammonium derivative(s) of the bicycloheptane derivatives of formula I as well as ÄanÜ optical isomer(s) thereof and mixtures of the optical isomers for preparing medicaments for the treatment of diseases and disorders which are connected with the influence on the peripheral cholecystokinin (CCK) system.