| 发明名称 |
METHODS FOR SELECTIVELY MODULATING SURVIVIN APOPTOSIS PATHWAYS |
| 摘要 |
The present invention, based on the discovery of a new biological phenomena, provides methods and compositions for use in identifying agents that modulate the phosphorylation of survivin, the interaction between survivin and p34<cdc2>-cyclin B1 kinase complex, and the interaction between survivin and caspase-9. Related methods and compositions can be used to modulate survivin regulated apoptosis.
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| 申请公布号 |
WO0164741(A2) |
申请公布日期 |
2001.09.07 |
| 申请号 |
WO2001US06341 |
申请日期 |
2001.02.28 |
| 申请人 |
YALE UNIVERSITY;ALTIERI, DARIO, C. |
发明人 |
ALTIERI, DARIO, C. |
| 分类号 |
A61K31/711;A61K38/00;A61K45/00;A61K48/00;A61P35/00;A61P43/00;C07K16/18;C12N1/00;C12Q1/02;C12Q1/48;G01N33/15;G01N33/50;G01N33/53;G01N33/573;(IPC1-7):C07K14/47 |
主分类号 |
A61K31/711 |
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