发明名称 |
THIENYLAZOLYLALCOXYETHANAMINES, THEIR PREPARATION AND THEIR APPLICATION AS MEDICAMENTS |
摘要 |
<p>The thienylazolylalcoxyethanamines (I) wherein R1 is a hydrogen atom, a halogen or a lower alkyl radical; R2, R3 and R4 represent independently a hydrogen atom or a lower alkyl radical; and Az is a 5-member nitrogenated aromatic N-methyl substituted heterocycle which contains from one to three nitrogen atoms, have an analgesic activity in mammals, including human beings. The compounds (I) can be obtained for example by reacting a hydroxythienylazol derivative (IV) with a derivative of an appropriate N-(ethyl)amine. The compound (IV) are useful intermediates for the synthesis of the compounds (I). The compounds (I) can be applied to human and/or veterinary medicine.</p> |
申请公布号 |
SI20473(A) |
申请公布日期 |
2001.08.31 |
申请号 |
SI19990020030 |
申请日期 |
1999.04.15 |
申请人 |
LABORATORIOS DEL DR. ESTEVE, S.A. |
发明人 |
MERCE-VIDAL RAMON;ANDALUZ-MATARO BLAS;FRIGOLA CONSTANSA JORDI |
分类号 |
A61K31/381;A61K31/401;A61K31/4155;A61P25/04;A61P29/00;A61P43/00;C07D231/00;C07D231/12;C07D333/00;C07D333/16;C07D409/04;C07D409/06;(IPC1-7):C07D409/06;A61K31/415 |
主分类号 |
A61K31/381 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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