Treatment of dermal tumors, warts, and viral infections using heat-killed p. acnes

摘要

Heat-killed, terminally sterilized saline suspensions of Propionibacterum acnes, Propionibacterium avidum, Propionibacterium lymphophylum, Propionibacterium granulosum, Cornynebacterium parvum, and Arachnia propionica are effective in treating viral infections of the respiratory tract in humans, and to induce the regression of dermal tumors and warts in humans. The potency of a saline suspension of heat-killed, terminally sterilized saline suspension of Propionibacterium acnes (P. acnes) was demonstrated through a laboratory animal challenge model. The P. acnes product is administered orally for the purpose of preventing or treating viral infections of the respiratory tract in man. The P. acnes preparation is intralesionally administered into dermal tumors, warts such as plantar warts, or other warts in people caused by the human papilloma virus, to cause regression of such dermal tumors and warts. The subcutaneous route of administration of the P. acnes product causes a systemic reaction that causes long-term warts to completely regress. Anesthetics such a Lidocaine may be added to the P. acnes product to prevent pain upon injection of this immune modulating preparation, while retaining the potency of the P. acnes product. Dose ranges have been established for the oral administration of the P. acnes product to treat viral infections, and for the subcutaneous and intralesional administration of the P. acnes product to treat dermal tumors and warts.