| 摘要 |
Methods and compositions for the control of nematodes are disclosed, using compounds of formula (47), wherein R1 is aryl (optionally substituted with OC1-5, halogen, phenyl or NO2); arylacetal (optionally substituted with NO2); C1-10 straight or branched alkyl; naphthyl; furan; or thiophene; C1-15 phenyl ether; R2 is C1-10 alkyl (optionally substituted with aryl (optionally substituted with halogen); aryl (optionally substituted with halogen, OC1-5 alkyl, amine, or OC1-5 Ar); or C1-10 branched or straight alkyl; R3 is aryl (optionally substituted with OC1-5); C1-10 straight or branched alkyloptionally substituted with morpholine; pyrrole; pyrrolidone; C1-5 phenyl ether; or ArOCF3); aryl (optionally substituted with halogen OC1-5 alkyl(optionally halogenated) or C1-5 alkyl; amine (optionally substituted with H, C1-5 alkyl or aryl)); C2-8 alcohol with ether linkage; heterocycle (optionally substituted with carbonyl), or C3-8 cycloalkyl (optionally substituted with alcohol); R4 is H, or C1-5 straight or branched alkyl; or R3 and R4 form a heterocycle (optionally substituted with NO2, NO2C1-5 or NOC1-5). The subject anthelmintic compounds have been found to advantageously control nematodes at concentrations which are non-phytotoxic. The anthelmintic compounds can be used in conjunction with other nematicidal agents such as free fatty acids, fatty acid salts, avermectins, ivermectin, and milbemycin. In another embodiment, the subject invention further provides methods for killing the eggs of nematodes. Thus, the subject invention further relates to the surprising discovery that certain compounds have ovicidal activity against nematode eggs.
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