CHIMERIC MOLECULES CONSISTING OF PSORALEN AND RETINOID, PREPARATION METHOD, USES THEREOF FOR TREATING CELL HYPERPROLIFERATION PATHOLOGIES AND IN PARTICULAR PSORIASIS

摘要

The invention concerns novel chimeric molecules having a cytotoxic and/or phytocytotoxic activity consisting of at least a retinoid molecule covalently bound via a linking arm to a psoralen molecule or one of its derivatives. The invention also concerns the method for preparing said molecules and their use for treating cell hyperproliferation pathologies, and in particular in PUVA treatment of psoriasis.