发明名称 |
Nucleic acid constructs whose activity is affected by inhibitors of cyclin-dependent kinases and uses thereof |
摘要 |
The present application discloses nucleic acid constructs comprising nucleic acids which encode a protein which inhibits the cellular protein p27 and thereby relieves the inhibition of the proliferation of the cell which is brought about by p27, fragments and variants thereof, some of which possess a dominant interfering character.
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申请公布号 |
US6265562(B1) |
申请公布日期 |
2001.07.24 |
申请号 |
US19980215221 |
申请日期 |
1998.12.18 |
申请人 |
AVENTIS PHARMA DEUTSCHLAND GMBH |
发明人 |
EILERS MARTIN;BUERGIN ANDREA;SEDLACEK HANS-HARALD |
分类号 |
C12N15/09;A61K31/00;A61K38/00;A61K38/17;A61K38/22;A61K38/43;A61K39/395;A61K48/00;A61P5/00;A61P7/00;A61P7/06;A61P9/00;A61P19/00;A61P19/02;A61P25/00;A61P29/00;A61P35/00;A61P35/02;A61P37/00;A61P37/02;A61P37/08;C07K14/435;C07K14/47;C07K16/18;C12N1/38;C12N15/12;C12N15/63;C12N15/79;C12N15/85;C12Q1/68;G01N33/15;G01N33/53;G01N33/566;G01N33/574;(IPC1-7):C07H21/04;C07H21/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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