COMPOSITIONS AND METHODS FOR EFFICIENT AAV VECTOR PRODUCTION
摘要
The present invention provides packaging cell lines for the efficient production of an Adeno-associated virus (AAV) vector which does not require "helper" virus function for the replication and encapsidation of the AAV vector particles. Packaging cells, methods for their production and methods for producing recombinant AAV vector particles useful for human gene therapy are provided.
申请公布号
WO0149829(A1)
申请公布日期
2001.07.12
申请号
WO2001US00429
申请日期
2001.01.05
申请人
FRED HUTCHINSON CANCER RESEARCH CENTER;MILLER, ARTHUR, DUSTY;ALLEN, JAMES, M.;HALBERT, CHRISTINE, L.
发明人
MILLER, ARTHUR, DUSTY;ALLEN, JAMES, M.;HALBERT, CHRISTINE, L.