MALLEABLE PASTE FOR FILLING BONE DEFECTS

摘要

The invention is directed toward a malleable bone putty and a flowable g el composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of demineralized lyophilized allograft bone powder. The bone powder has a particle size ranging from about 100 to about 850 microns and is mixed in a high molecular weight hydrogel carrier, the hydrogel component of the carrier ranging from about 0.3 to 3.0% of the composition and having a molecular weight of about at least 10,000 Daltons. The composition contains about 25% to about 4 0% bone powder and can be additionally provided with BMP's and a sodium phosphate buffer.