| 摘要 |
PROBLEM TO BE SOLVED: To provide a medicine for preventing or treating diseases related to inflammatory cytokine. SOLUTION: There is provided a medicine for preventing or treating diseases related to inflammatory cytokine, containing a compound of the general formula (I) A is a heteroaryl; Ar1 and Ar2 are each an aryl or a heteroaryl; Q is a (hetero)arylene or a divalent heterocyclic group; R1 is H, an alkyl, an alkenyl, an alkynyl, a halogen or nitro; R2 is H, an alkyl, an alkenyl or an alkynyl R3 is WR4 [W is an alkylene or the like; R4 is azido, nitro, nitrosooxy, nitrooxy, thiocyanato, PO(OR6)(OR7), C(=NOR8)R9 or CON(OR8)R9; R5, R8 and R9 are each H, an alkyl, an alkenyl, an alkynyl, an aryl, an aralkyl, a heteroaryl, a heteroarylalkyl or a protecting group; R6 and R7 are each H, an alkyl an alkenyl, an alkynyl, an aryl or an aralkyl]}.
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