TETANUS VACCINE PRODUCTION.

摘要

PCT No. PCT/GB93/01037 Sec. 371 Date Mar. 1, 1995 Sec. 102(e) Date Mar. 1, 1995 PCT Filed May 20, 1993 PCT Pub. No. WO94/03206 PCT Pub. Date Feb. 17, 1994A process for the preparation of tetanus toxoid, which process comprises incubating purified tetanus toxin with 0.2 to 1% (v/v) formaldehyde in the presence of 0.005 to 0.25M lysine for from 24 to 32 days at a pH of from 6.0 to 8.0 and a temperature of from 30 to 45 DEG C.