THE USE OF EXCITATORY AMINO ACID TRANSPORTER INHIBITORS TO REDUCE CNS WHITE MATTER INJURY

摘要

This invention provides a method of reducing the damaging effect of CNS white matter injury (including traumatic CNS injury, anoxia, and ischemia) to mammalian CNS tissue, particularly spinal cord tissue, by in vivo treatment thereof with inhibitors of excitatory amino acid transporters, such as the Na<+>-dependent glutamate transporter and pharmaceutical compositions comprising said inhibitors.