| 发明名称 |
HSV strain lacking functional ICP27 and ICP34.5 genes |
| 摘要 |
The present invention provides a herpes simplex virus strain which lacks a functional ICP34.5 gene and a functional ICP27 gene. It also provides the use of a herpes simplex virus strain which lacks a functional ICP34.5 gene and a functional ICP27 gene in the treatment of disorders of, or injuries to, the nervous system of a mammal.
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| 申请公布号 |
US6248320(B1) |
申请公布日期 |
2001.06.19 |
| 申请号 |
US19990230479 |
申请日期 |
1999.06.10 |
| 申请人 |
UNIVERSITY COLLEGE LONDON;THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW |
发明人 |
COFFIN ROBERT STUART;LATCHMAN DAVID SEYMOUR;MACLEAN ALASDAIR RODERICK;BROWN SUZANNE MOIRA |
| 分类号 |
C12N15/00;A61K35/30;A61K35/34;A61K48/00;A61P25/00;A61P25/16;A61P35/00;C07K14/035;C12N1/21;C12N7/04;C12N15/869;C12R1/01;(IPC1-7):A01N63/00;C12N7/00 |
主分类号 |
C12N15/00 |
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