发明名称 Improved storage and maintenance of blood products using a solution of L-carnitine or a derivative
摘要 A method of improving membrane maintenance and suppressing hemolysis on storage of platelet concentrate comprises suspending the platelet concentrate in a support solution comprising L-carnitine, alkanoyl L-carnitines or pharmacologically acceptable salts thereof or mixtures thereof, in an amount effective to improve the ability of the platelet concentrate to maintain the membrane of the platelets, and to thereby suppress hemolysis, as compared with an identical support solution lacking the L-carnitine, alkanoyl L-carnitines or pharmacologically acceptable salts thereof or mixtures thereof. A sealed container, which contains a platelet concentrate in a stabilizing solution comprising L-carnitine, alkanoyl L-carnitines or mixtures thereof in an amount of 0.25-50 mM.
申请公布号 NZ500534(A) 申请公布日期 2001.05.25
申请号 NZ19980500534 申请日期 1998.04.15
申请人 SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S 发明人 DOTTORI, SECONDO
分类号 A61J3/00;A01N1/02;A61L2/00;C12N5/02;C12N7/01;(IPC1-7):A01N1/02;A61L2/16;A61L2/08 主分类号 A61J3/00
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