Phenyl heterocyclic derivatives, process of their preparation and pharmaceutical preparations in which they are comprised

摘要

In the present invention there are disclosed phenyl heterocyclic derivatives of the general formula I, in which Re1 represents the group {SOi2CHi3} or the group {SOi2NHi2}, Re2 represents a mono- or disubstituted phenyl and substituents are selected from a group comprising methyl, methoxy, a hydrogen, fluorine, chlorine or bromine atom. The derivatives are inhibitors of cyclooxygenßse-2 and they are therefore suitable for treating diseases mediated by the action of this enzyme. The present invention also relates to pharmaceutical preparations containing these derivatives, use of such derivatives for preparing pharmaceutical preparations exhibiting non-steroidal antiphlogistic activity as well as processes for preparing the derivatives of the general formula I.