ARYL- AND HETEROARYL-SUBSTITUTED TETRAHYDROISOQUINOLINES ANDUSE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE AND SEROTONIN

摘要

Provided herein are compounds of formula (I), wherein R1-R8 are as described herein, R4 being aryl or heteroaryl. Such compounds are particularly useful in the treatment of a disorder which is created by or is dependent upon decreas ed availability of serotonin, norepinephrine or dopamine.