发明名称 |
METHOD FOR MASS-PURIFYING AND ACTIVATING NONSTRUCTURAL PROTEIN 3 DELTA OF HEPATITIS C VIRUS |
摘要 |
PURPOSE: Provided are method for purifying and activating nonstructural protein 3 delta of hepatitis C being essential in development of inhibitors of nonstructural protein 3 in large quantity and used as a therapeutic agent for hepatitis C. CONSTITUTION: A method for mass-purifying nonstructural protein 3 delta of hepatitis C virus is composed of following steps of: (a) accepting an inactivated inclusion body including nonstructural protein 3 delta of hepatitis C expressed in E.coli and formed by crushing E.coli cells and centrifuging lysates; and (b) activating and separatiing nonstructural protein 3 delta of hepatitis C virus.
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申请公布号 |
KR100293967(B1) |
申请公布日期 |
2001.04.10 |
申请号 |
KR19970060517 |
申请日期 |
1997.11.17 |
申请人 |
LG CHEM INVESTMENT, LTD. |
发明人 |
LEE, TAE GYU;MIN, CHANG HUI;OH, YEONG RIM |
分类号 |
C07K14/18;(IPC1-7):C07K14/18 |
主分类号 |
C07K14/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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